A review on bioscaffolds for tissue engineering application
نویسنده
چکیده
This paper reviews the current practices in the field of Tissue Engineering for Bone scaffold Applications. The mechanism of bone replacement or bone graft has been covered. The synthetic biomaterials and composites that are used for fabrication of scaffolds are reviewed. Scaffold requirements in terms of their mechanical properties, pore structure along with other biological properties are discussed. Finally, this paper also highlights the challenges faced in this industry and suggestions for further research and development of this field.
منابع مشابه
Bioscaffolds in tissue engineering: a rationale for use in the reconstruction of musculoskeletal soft tissues.
Bioscaffolds derived from animal tissues can be an appealing substrate to induce the formation of functional tissue (histogenesis) within the context of tissue engineering. Bioscaffolds obtained from the extracellular matrix not only contain collagen, which can provide mechanical support, but also include the required biologically active molecules that provide a stimulus for active tissue remod...
متن کاملNative extracellular matrix: a new scaffolding platform for repair of damaged muscle
Effective clinical treatments for volumetric muscle loss resulting from traumatic injury or resection of a large amount of muscle mass are not available to date. Tissue engineering may represent an alternative treatment approach. Decellularization of tissues and whole organs is a recently introduced platform technology for creating scaffolding materials for tissue engineering and regenerative m...
متن کاملProcess-induced extracellular matrix alterations affect the mechanisms of soft tissue repair and regeneration
Extracellular matrices derived from animal tissues for human tissue repairs are processed by various methods of physical, chemical, or enzymatic decellularization, viral inactivation, and terminal sterilization. The mechanisms of action in tissue repair vary among bioscaffolds and are suggested to be associated with process-induced extracellular matrix modifications. We compared three non-cross...
متن کاملReview Paper: Embryonic Stem Cell and Osteogenic Differentiation
Bone tissue engineering has been one of the most promising areas of research, providing a potential clinical application to cure bone defects. Recently, various stem cells, including embryonic stem cells (ESCs), bone marrow-derived mesenchymal stem cells (BM-MSCs), umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs), adipose tissue-derived stem cells (ADSCs), muscle-derived stem cell...
متن کاملApplication of Nanoscaffolds and Mesenchymal Stem Cells in Tissue Engineering
Stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. Mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. Today, nanofibrous scaffolds are widely used in tissue en...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014